

 
 Legal Sidebari 
 
Appellate Courts Split on Legal Challenges to 
State Laws Banning Certain Medical 
Treatments for Transgender Minors 
October 13, 2023 
Public debate and attention has focused on whether certain medical treatments should be available for 
transgender minors to address a discordance between a person’s sex characteristics and gender identity. A 
number of states have passed laws prohibiting specific treatments for minors, including puberty blocking 
medication (“puberty blockers”), hormones, and surgical procedures. Several states assert, among other 
things, that the treatments are too experimental and can have potentially irreversible effects. Parents of 
transgender minors, among others, argue that these laws deny critical medical care to transgender minors 
and discriminate based on sex or transgender status in violation of the Equal Protection Clause of the 
Fourteenth Amendment. Some litigation has also alleged that these laws violate state constitutions. 
In cases challenging the laws of Arkansas, Alabama, Tennessee, and Kentucky, plaintiffs sought federal 
court orders to preliminarily enjoin these states from enforcing the laws until final resolution of the cases. 
Several lower courts granted these preliminary injunctions, in part based on the conclusion that the 
plaintiffs were likely to succeed on the merits of their equal protection claims. Recently, three federal 
courts of appeals analyzed whether the lower courts had erred in their rulings and reached different 
conclusions. The Eighth Circuit upheld a preliminary injunction of Arkansas’s law, while the Eleventh 
Circuit held that a district court erred in enjoining the Alabama law, and the Sixth Circuit reversed 
preliminary injunctions that were issued against the Kentucky and Tennessee laws. 
This Sidebar focuses on aspects of these appellate court decisions addressing whether plaintiffs are likely 
to prevail on their claims that the laws violate the Equal Protection Clause. The courts reached different 
conclusions on at least two important legal questions relevant to the issue: (1) whether the challenged 
laws amount to sex classifications within the meaning of the Equal Protection Clause, and (2) what 
standard of review a court should apply when analyzing these challenges. The courts’ analyses of these 
questions are consequential, as the likelihood of a state action being upheld or invalidated under the Equal 
Protection Clause may turn significantly on how a court resolves them. These recent decisions not only 
dictate how lower courts within these circuits analyze equal protection challenges relating to transgender 
persons, but also may inform other courts’ approaches to similar equal protection challenges.  
Congressional Research Service 
https://crsreports.congress.gov 
LSB11057 
CRS Legal Sidebar 
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Equal Protection Background 
The Fourteenth Amendment’s Equal Protection Clause prohibits states from denying individuals “the 
equal protection of the laws.” In the most general terms, states must not classify or differentiate among 
similarly situated individuals in a manner that violates this constitutional guarantee. When analyzing an 
equal protection challenge, a court must first determine which legal standard to apply. The most 
deferential standard of equal protection review is rational basis, under which a court will generally uphold 
a challenged classification as long as it is reasonably related to a legitimate government purpose. Courts 
subject classifications based on sex, however, to a more stringent standard—intermediate scrutiny. If 
intermediate scrutiny applies, the parties seeking to defend a sex-based classification must show an 
“exceedingly persuasive justification” or “important government interest” for classifying individuals 
based on sex and must demonstrate that the classification is “substantially related” to achieving that 
interest.  
In equal protection challenges raised in another context—school restroom access—several federal 
appellate courts have concluded that laws prohibiting transgender individuals from access consistent with 
their gender identity amount to sex-based classifications subject to intermediate scrutiny. In addition, at 
least two appellate courts have also held that transgender individuals constitute a quasi-suspect class for 
equal protection purposes—that is, a class of individuals who warrant heightened protection under the 
law—and that transgender-based classifications are subject to intermediate scrutiny on that basis.  
Challenges to State Laws in Federal Appellate Courts  
When analyzing the legal bases for the preliminary injunctions at issue, the appellate courts considering 
the challenges to the Arkansas, Tennessee, Kentucky, and Alabama laws differed on the applicable 
standard of review. The Eighth Circuit construed the Arkansas law as classifying individuals based on 
sex, held that intermediate scrutiny applied, and concluded it was likely that the plaintiffs would prevail 
on their claim. By contrast, both the Sixth and Eleventh Circuits held that rational basis review applied 
and that the challenged laws neither contained a sex classification nor targeted a quasi-suspect class. (The 
Sixth and Eleventh Circuits also rejected arguments related to the Due Process Clause of the Fourteenth 
Amendment, further discussion of which is beyond the scope of this Sidebar.) 
Eighth Circuit: Brandt v. Rutledge 
The Eighth Circuit affirmed a district court’s preliminary injunction of Arkansas’s law banning “gender 
transition procedures” for minors, reasoning that the law was a sex classification that did not satisfy 
intermediate scrutiny. Arkansas’s law bans procedures and drugs intended to remove or alter “physical or 
anatomical characteristics or features that are typical for the individual’s biological sex” or “create 
physiological or anatomical characteristics that resemble a sex different from the individual’s biological 
sex.” Specific medical services identified in the law include puberty blockers, “cross-sex hormones,” and 
“gender reassignment surgery.” Prohibited procedures do not include those for individuals “born with a 
medically verifiable disorder of sex development.” 
Reviewing the injunction, the Eighth Circuit reasoned that the law discriminates on the basis of sex 
because medical procedures permitted for minors of one sex are denied to minors of another sex. For 
instance, a minor born as a male can be prescribed testosterone, but a minor born as a female is not 
permitted to receive that treatment. The court thus viewed the law as subject to intermediate scrutiny. The 
state’s asserted justification for the law was its interest in protecting minors from “experimental medical 
treatment” and regulating medical ethics. The Eighth Circuit concluded that there was substantial 
evidence to support the district court’s findings that the medical treatments were a recognized standard of 
care and “supported by medical evidence … subject to rigorous study.” The Eighth Circuit accordingly 
  
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determined that the lower court was not wrong to conclude the law’s prohibition was likely to fail 
intermediate scrutiny, as it was not substantially related to the state’s interest in protecting minors from 
experimental treatment and regulation of medical ethics. 
The full Eighth Circuit later denied a petition for rehearing en banc, with five judges dissenting from the 
denial and several others indicating that an appeal from a final judgment would offer the court a more 
comprehensive record to review. Following a trial in the case, the district court entered a permanent 
injunction against enforcement of the law, and that decision is now pending before the Eighth Circuit, 
which has granted a petition for an initial hearing en banc. 
Eleventh Circuit: Eknes-Tucker v. Governor of Alabama 
In contrast to the Eighth Circuit’s analysis in Brandt, the Eleventh Circuit held that specific provisions of 
a similar Alabama law did not amount to a sex-based or quasi-suspect classification for equal protection 
purposes. The court concluded that the challenged provisions were “best understood as a law that targets 
specific medical interventions for minors,” or as classifying based on age, and that it was “exceedingly 
likely” that the provisions satisfied rational basis review.   
The challenged provisions of Alabama’s law prohibit any person from prescribing or administering 
“puberty blocking medication,” “supraphysiologic doses of testosterone or other androgens to females,” 
and “supraphysiologic doses of estrogen to males,” when given “to attempt[] to alter the appearance of or 
affirm the minor’s perception of his or her gender or sex, if that appearance or perception is inconsistent 
with the minor’s sex as defined in this act.” The law’s other provisions, which were not challenged in the 
Eknes-Tucker lawsuit, include a prohibition of specific surgical procedures. The Alabama law defines a 
minor as a person under the age of 19, and defines sex to mean “‘[t]he biological state of being male or 
female, based on the individual’s sex organs, chromosomes, and endogenous hormone profiles.’”  
The Eleventh Circuit rejected the plaintiffs’ assertion that the provisions classify based on sex because the 
law uses sex-based terms to criminalize certain treatments. The law refers to sex, the court decided, only 
because the medical interventions at issue concern physiological sex characteristics. “[I]t is difficult to 
imagine how a state might regulate the use of puberty blockers and cross-sex hormones . . . in specific 
terms without referencing sex in some way,” the court observed. More significantly, the court reasoned 
that the challenged provisions do not distinguish between men and women by denying an opportunity to 
one sex but not the other—a key feature of sex-based classifications for equal protection purposes. Rather, 
in the court’s view, the restrictions on puberty blockers and hormone treatment apply to all minors, 
regardless of sex. The appellate court also rejected the argument, adopted by the lower court, that a 
classification based on gender nonconformity “indirectly classifies on the basis of sex.” The appellate 
court held that the lower court had relied on inapposite precedent to reach that conclusion, including a 
Supreme Court decision interpreting Title VII of the Civil Rights Act of 1964. That decision, the court 
reasoned, addressed a federal statute, not the different text and meaning of the Equal Protection Clause, 
and did not concern the regulation of medical treatments. The Eleventh Circuit also rejected the view that 
transgender persons constitute a quasi-suspect class distinct from sex. 
The court did observe that the challenged provisions prohibit medical treatment for minors that only 
gender nonconforming or transgender individuals would want to undergo. Addressing that distinction, the 
court stated that the law would trigger heightened scrutiny if regulating medical treatment were “a pretext 
for invidious discrimination against such individuals.” In the case before the court, however, “the district 
court did not find that Alabama’s law was based on invidious discrimination.” Nor did the challenged 
provisions “further any particular gender stereotype.” Rather, the provisions, in the court’s view, refer to 
and “reflect[] biological differences between males and females.” In a concurring opinion, Judge Brasher 
agreed that rational basis review was the applicable standard but added that even if intermediate scrutiny 
  
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applied to the challenged provisions of Alabama’s law, it was likely the state would satisfy that standard. 
The plaintiffs have filed a petition seeking en banc review of the panel decision. 
Sixth Circuit: Williams v. Skrmetti 
The Sixth Circuit reached a similar result in two separate cases where district courts granted preliminary 
injunctions against Tennessee’s and Kentucky’s laws addressing hormones and puberty blockers. After 
analyzing each injunction in separate initial rulings, the Sixth Circuit later issued a decision reversing 
both injunctions. The Tennessee law bans certain medical treatments for minors that have the purpose of 
enabling identification with “a purported identity inconsistent with the minor’s sex,” or addressing 
“purported discomfort or distress from a discordance between the minor’s sex and asserted identity.” 
Prohibited medical treatments include puberty blockers, hormones, and surgery. Similarly, Kentucky bars 
medical providers from offering treatments “for the purpose of attempting to alter the appearance of, or to 
validate a minor’s perception of, the minor’s sex, if that appearance or perception is inconsistent with the 
minor’s sex.” Specifically prohibited treatments include puberty blockers, hormones, and surgery.  
The Sixth Circuit ruled that the laws do not discriminate based on sex and thus were not subject to 
heightened scrutiny. In an opinion by Chief Judge Sutton, the panel majority ruled that the challenged 
provisions limit access to treatments for all children equally, “regardless of sex,” and treat “similarly 
situated individuals evenhandedly.” The “key to the constitutionality” of the Tennessee and Kentucky 
state laws, in the court’s view, was “that they do not disadvantage ‘persons’ based on their sex.” Rather, 
whether these treatments are available to someone turns on “the age of the individual and the risk-reward 
assessment of treating this medical condition.” Pointing to Supreme Court equal protection cases that had 
found sex classifications, the Sixth Circuit distinguished the state laws at issue, concluding that they do 
not prefer one sex to another, exclude one sex and include another, or distribute burdens or benefits based 
on sex. 
The plaintiffs argued that the laws do treat minors differently based on their sex—triggering heightened 
scrutiny—because, for example, while a boy with abnormally low testosterone levels could be treated 
with testosterone under the laws, a girl seeking to transition could not. The court rejected this argument, 
pointing to Dobbs v. Jackson Women’s Health Organization, in which the Supreme Court determined that 
laws which regulate “a medical procedure that only one sex can undergo” (such as pregnancy) do not 
trigger heightened constitutional scrutiny. The Sixth Circuit reasoned that by “biological necessity,” these 
hormone treatments are procedures “that only one sex can undergo.” Overall, the court concluded that 
“the States treat boys and girls exactly the same for constitutional purposes—reasonably limiting 
potentially irreversible procedures until they become adults.” The court also declined to apply heightened 
scrutiny under the theory that transgender individuals constitute a quasi-suspect class. The court observed 
that neither the Supreme Court nor the Sixth Circuit has recognized transgender status as a quasi-suspect 
class, and the bar for recognizing a new quasi-suspect class is high.  
Applying rational basis review, the court concluded that the laws satisfied that standard. The Sixth Circuit 
observed that the “unsettled, developing, ... experimental[] nature of treatments in this area surely permits 
more than one policy approach.” The court concluded that the states “offered considerable evidence about 
the risks of these treatments and the flaws in existing research,” and the challengers’ disagreement with 
the states’ assessment of the risks and proper response was not sufficient to invalidate the laws on rational 
basis review. The court concluded by emphasizing that it did not doubt the existence of gender dysphoria 
or the value of providing “psychological and related care to children facing it,” but judges should exercise 
particular caution when asked to overrule or interfere with the policy decisions of legislatures in an 
evolving medical area. The panel decision drew a dissent from Judge White. Judge White reasoned that 
the laws discriminate on the basis of sex and trigger intermediate scrutiny. Applying intermediate scrutiny, 
Judge White concluded that the laws “rested on improper generalizations about boys and girls” and that 
their apparent purpose of protecting minors was not served by the classifications. 
  
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Considerations for Congress  
The level of scrutiny that a court applies in an equal protection challenge can have crucial implications for 
the outcome of a case. A court that construes a ban on certain medical treatments for transgender minors 
as a sex-based classification, or that concludes transgender persons constitute a quasi-suspect status, is 
more likely to invalidate a challenged law. In addition, as federal courts continue to address equal 
protection challenges, it may be that this precedent develops differently depending on the specific context 
at issue. Among other things, the asserted government interest at stake in an equal protection case, and the 
strength of that interest, can vary from case to case. For instance, unlike the appellate court decisions 
addressing the use of bathroom facilities by transgender students, where the asserted government interest 
in denying access has been the protection of student privacy, the Eleventh Circuit in Eknes-Tucker found 
that the challenged Alabama provisions were supported by the state’s compelling interest in “safeguarding 
the physical and psychological well-being” of minors.  
These considerations could have implications for federal statutes and regulations that may address 
discrimination against transgender individuals. Congress possesses authority to amend these statutes and 
to direct federal agencies in promulgating regulations that interpret them. For instance, Title IX of the 
Education Amendments of 1972 prohibits discrimination “on the basis of sex” in federally funded 
education programs, subject to various statutory exemptions. Section 1557 of the Affordable Care Act 
prohibits discrimination on various bases in federally funded health programs. Two federal agencies 
issued Notices of Proposed Rulemaking on Section 1557 and Title IX last year, proposing to construe 
these statutes to prohibit certain actions based on transgender status, including the denial of certain 
medical treatments. As equal protection precedent continues to develop, Congress could amend these 
statutes’ prohibitions or exceptions or direct agencies to amend their implementing regulations. 
 
Author Information 
 
Christine J. Back 
  Jared P. Cole 
Legislative Attorney 
Legislative Attorney  
 
 
 
 
 
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